Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks

SB 9200, an orally bioavailable dinucleotide, activates the viral sensor proteins, retinoic acid-inducible gene 1 (RIG-I) and nucleotide-binding oligomerization domain-containing protein 2 (NOD2) causing the induction of the interferon (IFN) signaling cascade for antiviral defense. The present study...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Suresh, Manasa, Korolowicz, Kyle E., Balarezo, Maria, Iyer, Radhakrishnan P., Padmanabhan, Seetharamaiyer, Cleary, Dillon, Gimi, Rayomand, Sheri, Anjaneyulu, Yon, Changsuek, Kallakury, Bhaskar V., Tucker, Robin D., Afdhal, Nezam, Menne, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215947/
https://ncbi.nlm.nih.gov/pubmed/28056062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169631
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