HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma

Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting its driving SS18-SSX fusion oncoprotein are currently available. Patients remain at high risk for early and late metastasis. A high-throughput drug screen consisting of over 900 tool co...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Laporte, Aimée N., Barrott, Jared J., Yao, Ren Jie, Poulin, Neal M., Brodin, Bertha A., Jones, Kevin B., Underhill, T. Michael, Nielsen, Torsten O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215898/
https://ncbi.nlm.nih.gov/pubmed/28056055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169407
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados