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Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model

Zika virus (ZIKV) is currently undergoing pandemic emergence. While disease is typically subclinical, severe neurologic manifestations in fetuses and newborns after congenital infection underscore an urgent need for antiviral interventions. The adenosine analog BCX4430 has broad-spectrum activity ag...

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Gepubliceerd in:Antiviral Res
Hoofdauteurs: Julander, Justin G., Siddharthan, Venkatraman, Evans, Joe, Taylor, Ray, Tolbert, Kelsey, Apuli, Chad, Stewart, Jason, Collins, Preston, Gebre, Makda, Neilson, Skot, Van Wettere, Arnaud, Lee, Young-Min, Sheridan, William P., Morrey, John D., Babu, Y.S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215849/
https://ncbi.nlm.nih.gov/pubmed/27838352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.11.003
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