Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430

Filoviruses are emerging pathogens and causative agents of viral haemorrhagic fever. Case fatality rates of filovirus disease outbreaks are among the highest reported for any human pathogen, exceeding 90% (ref. 1). Licensed therapeutic or vaccine products are not available to treat filovirus disease...

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Publicat a:Nature
Autors principals: Warren, Travis K., Wells, Jay, Panchal, Rekha G., Stuthman, Kelly S., Garza, Nicole L., Van Tongeren, Sean A., Dong, Lian, Retterer, Cary J., Eaton, Brett P., Pegoraro, Gianluca, Honnold, Shelley, Bantia, Shanta, Kotian, Pravin, Chen, Xilin, Taubenheim, Brian R., Welch, Lisa S., Minning, Dena M., Babu, Yarlagadda S., Sheridan, William P., Bavari, Sina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095208/
https://ncbi.nlm.nih.gov/pubmed/24590073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13027
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