A Target-Based Whole Cell Screen Approach To Identify Potential Inhibitors of Mycobacterium tuberculosis Signal Peptidase

[Image: see text] The general secretion (Sec) pathway is a conserved essential pathway in bacteria and is the primary route of protein export across the cytoplasmic membrane. During protein export, the signal peptidase LepB catalyzes the cleavage of the signal peptide and subsequent release of matur...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Infect Dis
Main Authors: Bonnett, Shilah A., Ollinger, Juliane, Chandrasekera, Susantha, Florio, Stephanie, O’Malley, Theresa, Files, Megan, Jee, Jo-Ann, Ahn, James, Casey, Allen, Ovechkina, Yulia, Roberts, David, Korkegian, Aaron, Parish, Tanya
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2016
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215716/
https://ncbi.nlm.nih.gov/pubmed/27642770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00075
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki