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Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target

Mycobacterium tuberculosis is a pathogen of major global importance. Validated drug targets are required in order to develop novel therapeutics for drug-resistant strains and to shorten therapy. The Clp protease complexes provide a means for quality control of cellular proteins; the proteolytic acti...

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Hlavní autoři: Ollinger, Juliane, O'Malley, Theresa, Kesicki, Edward A., Odingo, Joshua, Parish, Tanya
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264079/
https://ncbi.nlm.nih.gov/pubmed/22123255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06142-11
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