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Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target
Mycobacterium tuberculosis is a pathogen of major global importance. Validated drug targets are required in order to develop novel therapeutics for drug-resistant strains and to shorten therapy. The Clp protease complexes provide a means for quality control of cellular proteins; the proteolytic acti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264079/ https://ncbi.nlm.nih.gov/pubmed/22123255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06142-11 |
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