Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

Microglial clusters with C3d deposits are observed in the periplaque of multiple sclerosis (MS) brains and were proposed as early stage of lesion formation. As such they should appear in the brain of MS donors with acute disease but thus far this has not been shown. Using postmortem brain tissue fro...

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Dades bibliogràfiques
Publicat a:Glia
Autors principals: Michailidou, Iliana, Naessens, Daphne M. P., Hametner, Simon, Guldenaar, Willemijn, Kooi, Evert‐Jan, Geurts, Jeroen J. G., Baas, Frank, Lassmann, Hans, Ramaglia, Valeria
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215693/
https://ncbi.nlm.nih.gov/pubmed/27778395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23090
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