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Microglial Activation in the Pathogenesis of Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by expanded CAG trinucleotide repeats (>36) in exon 1 of HTT gene that encodes huntingtin protein. Although HD is characterized by a predominant loss of neurons in the striatum and cortex, previous st...
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| 出版年: | Front Aging Neurosci |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474461/ https://ncbi.nlm.nih.gov/pubmed/28674491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00193 |
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