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Microglial Activation in the Pathogenesis of Huntington’s Disease

Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by expanded CAG trinucleotide repeats (>36) in exon 1 of HTT gene that encodes huntingtin protein. Although HD is characterized by a predominant loss of neurons in the striatum and cortex, previous st...

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Podrobná bibliografie
Vydáno v:Front Aging Neurosci
Hlavní autoři: Yang, Hui-Ming, Yang, Su, Huang, Shan-Shan, Tang, Bei-Sha, Guo, Ji-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474461/
https://ncbi.nlm.nih.gov/pubmed/28674491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00193
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