Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

Microglial clusters with C3d deposits are observed in the periplaque of multiple sclerosis (MS) brains and were proposed as early stage of lesion formation. As such they should appear in the brain of MS donors with acute disease but thus far this has not been shown. Using postmortem brain tissue fro...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Michailidou, Iliana, Naessens, Daphne M. P., Hametner, Simon, Guldenaar, Willemijn, Kooi, Evert‐Jan, Geurts, Jeroen J. G., Baas, Frank, Lassmann, Hans, Ramaglia, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215693/
https://ncbi.nlm.nih.gov/pubmed/27778395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23090
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