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Short Enantioselective Total Synthesis of Tatanan A and 3‐epi‐Tatanan A Using Assembly‐Line Synthesis

Short and highly stereoselective total syntheses of the sesquilignan natural product tatanan A and its C3 epimer are described. An assembly‐line synthesis approach, using iterative lithiation–borylation reactions, was applied to install the three contiguous stereocenters with high enantio‐ and diast...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Noble, Adam, Roesner, Stefan, Aggarwal, Varinder K.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215435/
https://ncbi.nlm.nih.gov/pubmed/27865037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609598
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