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Enantioselective synthesis of tatanans A–C and reinvestigation of their glucokinase-activating properties

The tatanans are members of a novel class of complex sesquilignan natural products recently isolated from the rhizomes of Acorus tatarinowii Schott plants. Tatanans A, B and C have previously been reported to have potent glucokinase-activating properties that exceed the in vitro activity of known sy...

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Detalhes bibliográficos
Main Authors: Xiao, Qing, Jackson, Jeffrey J., Basak, Ashok, Bowler, Joseph M., Miller, Brian G., Zakarian, Armen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126512/
https://ncbi.nlm.nih.gov/pubmed/23609092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1597
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