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Perturbed proteostasis in autism spectrum disorders
Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes enc...
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| Pubblicato in: | J Neurochem |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215415/ https://ncbi.nlm.nih.gov/pubmed/27365114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13723 |
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