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Perturbed proteostasis in autism spectrum disorders
Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes enc...
Guardat en:
| Publicat a: | J Neurochem |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215415/ https://ncbi.nlm.nih.gov/pubmed/27365114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13723 |
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