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Perturbed proteostasis in autism spectrum disorders

Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes enc...

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Foilsithe in:J Neurochem
Main Authors: Louros, Susana R., Osterweil, Emily K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215415/
https://ncbi.nlm.nih.gov/pubmed/27365114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13723
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