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Subcellular Localizations of RIG-I, TRIM25, and MAVS Complexes

The retinoic acid-inducible gene 1 (RIG-I) signaling pathway is essential for the recognition of viruses and the initiation of host interferon (IFN)-mediated antiviral responses. Once activated, RIG-I interacts with polyubiquitin chains generated by TRIM25 and binds mitochondrial antiviral signaling...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Sánchez-Aparicio, M. T., Ayllón, J., Leo-Macias, A., Wolff, T., García-Sastre, A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215348/
https://ncbi.nlm.nih.gov/pubmed/27807226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01155-16
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