The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination

Severe acute respiratory syndrome (SARS) is a respiratory disease, caused by a coronavirus (SARS-CoV), that is characterized by atypical pneumonia. The nucleocapsid protein (N protein) of SARS-CoV plays an important role in inhibition of type I interferon (IFN) production via an unknown mechanism. I...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Hu, Yong, Li, Wei, Gao, Ting, Cui, Yan, Jin, Yanwen, Li, Ping, Ma, Qingjun, Liu, Xuan, Cao, Cheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375661/
https://ncbi.nlm.nih.gov/pubmed/28148787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02143-16
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