Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

Gene conversions resulting from meiotic recombination are critical in shaping genome diversification and evolution. How the extent of gene conversions is regulated is unknown. Here we show that the budding yeast mismatch repair related MutLβ complex, Mlh1-Mlh2, specifically interacts with the conser...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Duroc, Yann, Kumar, Rajeev, Ranjha, Lepakshi, Adam, Céline, Guérois, Raphaël, Md Muntaz, Khan, Marsolier-Kergoat, Marie-Claude, Dingli, Florent, Laureau, Raphaëlle, Loew, Damarys, Llorente, Bertrand, Charbonnier, Jean-Baptiste, Cejka, Petr, Borde, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215242/
https://ncbi.nlm.nih.gov/pubmed/28051769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21900
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