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Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice

Advanced age is one of the risk factors for vascular diseases that are mainly caused by impaired nitric oxide (NO) production. It has been demonstrated that endothelial arginase constrains the activity of endothelial nitric oxide synthase (eNOS) and limits NO generation. Hence, arginase inhibition i...

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Опубликовано в: :Korean J Physiol Pharmacol
Главные авторы: Nguyen, Minh Cong, Ryoo, Sungwoo
Формат: Artigo
Язык:Inglês
Опубликовано: The Korean Physiological Society and The Korean Society of Pharmacology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214914/
https://ncbi.nlm.nih.gov/pubmed/28066144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.1.83
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