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Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice

Advanced age is one of the risk factors for vascular diseases that are mainly caused by impaired nitric oxide (NO) production. It has been demonstrated that endothelial arginase constrains the activity of endothelial nitric oxide synthase (eNOS) and limits NO generation. Hence, arginase inhibition i...

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Vydáno v:Korean J Physiol Pharmacol
Hlavní autoři: Nguyen, Minh Cong, Ryoo, Sungwoo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214914/
https://ncbi.nlm.nih.gov/pubmed/28066144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.1.83
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