Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat

We investigated whether betulin affects the gene expression, secretion and proteolytic activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective effect of...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Korean J Physiol Pharmacol
المؤلفون الرئيسيون: Ra, Ho Jong, Lee, Hyun Jae, Jo, Ho Seung, Nam, Dae Cheol, Lee, Young Bok, Kang, Byeong Hun, Moon, Dong Kyu, Kim, Dong Hee, Lee, Choong Jae, Hwang, Sun-Chul
التنسيق: Artigo
اللغة:Inglês
منشور في: The Korean Physiological Society and The Korean Society of Pharmacology 2017
الموضوعات:
Original Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214907/
https://ncbi.nlm.nih.gov/pubmed/28066137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.1.19
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