Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes

We examined whether apigenin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the knee joint of rat to evaluate the potential chondroprotective effects of apigenin. R...

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Bibliographische Detailangaben
Veröffentlicht in:Biomol Ther (Seoul)
Hauptverfasser: Park, Jin Sung, Kim, Dong Kyu, Shin, Hyun-Dae, Lee, Hyun Jae, Jo, Ho Seung, Jeong, Jin Hoon, Choi, Young Lac, Lee, Choong Jae, Hwang, Sun-Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Applied Pharmacology 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774497/
https://ncbi.nlm.nih.gov/pubmed/26902085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.217
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