Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes

We examined whether apigenin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the knee joint of rat to evaluate the potential chondroprotective effects of apigenin. R...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Park, Jin Sung, Kim, Dong Kyu, Shin, Hyun-Dae, Lee, Hyun Jae, Jo, Ho Seung, Jeong, Jin Hoon, Choi, Young Lac, Lee, Choong Jae, Hwang, Sun-Chul
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774497/
https://ncbi.nlm.nih.gov/pubmed/26902085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.217
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