Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo

In the present study, we tried to examine whether oleanolic acid regulates the activity, secretion and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as the production of MMP-3 in the knee joint of rat to evaluate the potential chondr...

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Detalhes bibliográficos
Publicado no:Korean J Physiol Pharmacol
Main Authors: Kang, Dong-Geun, Lee, Hyun Jae, Kim, Kun Tae, Hwang, Sun-Chul, Lee, Choong Jae, Park, Jin Sung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343053/
https://ncbi.nlm.nih.gov/pubmed/28280413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.2.197
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