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CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modeling

The next-generation sequencing identifies a growing number of candidate genes associated with human genetic diseases, which inevitably requires efficient methods to validate the causal links between genotype and phenotype. Recently, zebrafish, with sufficiently high-throughput capabilities, has beco...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genet
Hauptverfasser: Liu, Jiaqi, Zhou, Yangzhong, Qi, Xiaolong, Chen, Jia, Chen, Weisheng, Qiu, Guixing, Wu, Zhihong, Wu, Nan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214880/
https://ncbi.nlm.nih.gov/pubmed/27807677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1739-6
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