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MBD4 Facilitates Immunoglobulin Class Switch Recombination
Immunoglobulin heavy chain class switch recombination (CSR) requires targeted formation of DNA double-strand breaks (DSBs) in repetitive switch region elements followed by ligation between distal breaks. The introduction of DSBs is initiated by activation-induced cytidine deaminase (AID) and require...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214850/ https://ncbi.nlm.nih.gov/pubmed/27777312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00316-16 |
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