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Complex Relationship between Mismatch Repair Proteins and MBD4 during Immunoglobulin Class Switch Recombination

Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR). Methyl CpG binding domain protein 4 (MBD4) binds to MutL homologue 1 (MLH1) and controls the post-transcriptional level of several MMR proteins, including MutS homologue 2...

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Detalles Bibliográficos
Main Authors: Grigera, Fernando, Bellacosa, Alfonso, Kenter, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812156/
https://ncbi.nlm.nih.gov/pubmed/24205214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078370
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