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Complex Relationship between Mismatch Repair Proteins and MBD4 during Immunoglobulin Class Switch Recombination

Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR). Methyl CpG binding domain protein 4 (MBD4) binds to MutL homologue 1 (MLH1) and controls the post-transcriptional level of several MMR proteins, including MutS homologue 2...

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Detalhes bibliográficos
Main Authors: Grigera, Fernando, Bellacosa, Alfonso, Kenter, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812156/
https://ncbi.nlm.nih.gov/pubmed/24205214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078370
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