Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

We report the three-dimensional structures, at 1.8-A resolution, of the Fv fragment of the anti-hen egg white lysozyme antibody D1.3 in its free and antigen-bound forms. These structures reveal a role for solvent molecules in stabilizing the complex and provide a molecular basis for understanding th...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bhat, T N, Bentley, G A, Boulot, G, Greene, M I, Tello, D, Dall'Acqua, W, Souchon, H, Schwarz, F P, Mariuzza, R A, Poljak, R J
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC521459/
https://ncbi.nlm.nih.gov/pubmed/8302837
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki