T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy

We herein report retargeting of T-helper (Th) cells against the universal cancer antigen telomerase for use in adoptive cell therapy. The redirected Th cells may counter tumor tolerance, transform the inflammatory milieu, and induce epitope spreading and cancer senescence. We have previously conduct...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Kyte, Jon Amund, Gaudernack, Gustav, Faane, Anne, Lislerud, Kari, Inderberg, Else Marit, Brunsvig, Paal, Aamdal, Steinar, Kvalheim, Gunnar, Wälchli, Sébastien, Pule, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214348/
https://ncbi.nlm.nih.gov/pubmed/28123886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1249090
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