Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial

BACKGROUND: Ipilimumab improves survival for patients with metastatic malignant melanoma. Combining a therapeutic cancer vaccine with ipilimumab may increase efficacy by providing enhanced anti-tumor immune responses. UV1 consists of three synthetic long peptides from human telomerase reverse transc...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Aamdal, Elin, Inderberg, Else Marit, Ellingsen, Espen Basmo, Rasch, Wenche, Brunsvig, Paal Fredrik, Aamdal, Steinar, Heintz, Karen-Marie, Vodák, Daniel, Nakken, Sigve, Hovig, Eivind, Nyakas, Marta, Guren, Tormod Kyrre, Gaudernack, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147687/
https://ncbi.nlm.nih.gov/pubmed/34046035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.663865
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