The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease in need of prognostic markers to address therapeutic choices. We have previously shown that alternative splicing of the actin regulator, hMENA, generates hMENA(11a), and hMENAΔv6 isoforms with opposite roles in cell invasion. We examin...

詳細記述

保存先:
書誌詳細
出版年:Oncoimmunology
主要な著者: Melchionna, Roberta, Iapicca, Pierluigi, Di Modugno, Francesca, Trono, Paola, Sperduti, Isabella, Fassan, Matteo, Cataldo, Ivana, Rusev, Borislav C., Lawlor, Rita T., Diodoro, Maria Grazia, Milella, Michele, Grazi, Gian Luca, Bissell, Mina J., Scarpa, Aldo, Nisticò, Paola
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2016
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213039/
https://ncbi.nlm.nih.gov/pubmed/28123868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1221556
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