The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease in need of prognostic markers to address therapeutic choices. We have previously shown that alternative splicing of the actin regulator, hMENA, generates hMENA(11a), and hMENAΔv6 isoforms with opposite roles in cell invasion. We examin...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Melchionna, Roberta, Iapicca, Pierluigi, Di Modugno, Francesca, Trono, Paola, Sperduti, Isabella, Fassan, Matteo, Cataldo, Ivana, Rusev, Borislav C., Lawlor, Rita T., Diodoro, Maria Grazia, Milella, Michele, Grazi, Gian Luca, Bissell, Mina J., Scarpa, Aldo, Nisticò, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213039/
https://ncbi.nlm.nih.gov/pubmed/28123868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1221556
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