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The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease in need of prognostic markers to address therapeutic choices. We have previously shown that alternative splicing of the actin regulator, hMENA, generates hMENA(11a), and hMENAΔv6 isoforms with opposite roles in cell invasion. We examin...

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Foilsithe in:Oncoimmunology
Main Authors: Melchionna, Roberta, Iapicca, Pierluigi, Di Modugno, Francesca, Trono, Paola, Sperduti, Isabella, Fassan, Matteo, Cataldo, Ivana, Rusev, Borislav C., Lawlor, Rita T., Diodoro, Maria Grazia, Milella, Michele, Grazi, Gian Luca, Bissell, Mina J., Scarpa, Aldo, Nisticò, Paola
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213039/
https://ncbi.nlm.nih.gov/pubmed/28123868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1221556
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