hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis

We demonstrated previously that the splicing of the actin regulator, hMENA, generates two alternatively expressed isoforms, hMENA(11a) and hMENAΔv6, which have opposite functions in cell invasiveness. Their mechanisms of action have remained unclear. Here we report two major findings: (i) hMENA regu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Di Modugno, Francesca, Spada, Sheila, Palermo, Belinda, Visca, Paolo, Iapicca, Pierluigi, Di Carlo, Anna, Antoniani, Barbara, Sperduti, Isabella, Di Benedetto, Anna, Terrenato, Irene, Mottolese, Marcella, Gandolfi, Francesco, Facciolo, Francesco, Chen, Emily I., Schwartz, Martin A., Santoni, Angela, Bissell, Mina J., Nisticò, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193944/
https://ncbi.nlm.nih.gov/pubmed/29907768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0364-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados