लोड हो रहा है...
MutS inhibits RecA-mediated strand exchange with platinated DNA substrates
Human cell lines and Escherichia coli dam mutants are sensitive to the cytotoxic action of the anticancer agent, cisplatin. Introduction of mutations disabling DNA mismatch repair into these cell lines renders them resistant to the action of this drug. We used RecA-mediated strand exchange between h...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2004
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521133/ https://ncbi.nlm.nih.gov/pubmed/15375217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406104101 |
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