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MutS inhibits RecA-mediated strand exchange with platinated DNA substrates
Human cell lines and Escherichia coli dam mutants are sensitive to the cytotoxic action of the anticancer agent, cisplatin. Introduction of mutations disabling DNA mismatch repair into these cell lines renders them resistant to the action of this drug. We used RecA-mediated strand exchange between h...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521133/ https://ncbi.nlm.nih.gov/pubmed/15375217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406104101 |
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