Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma

Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC. Here, we analyze the whole transcriptomes and genomes of prim...

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Veröffentlicht in:mBio
Hauptverfasser: Starrett, Gabriel J., Marcelus, Christina, Cantalupo, Paul G., Katz, Joshua P., Cheng, Jingwei, Akagi, Keiko, Thakuria, Manisha, Rabinowits, Guilherme, Wang, Linda C., Symer, David E., Pipas, James M., Harris, Reuben S., DeCaprio, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210499/
https://ncbi.nlm.nih.gov/pubmed/28049147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02079-16
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