Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma

Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC. Here, we analyze the whole transcriptomes and genomes of prim...

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Publicat a:mBio
Autors principals: Starrett, Gabriel J., Marcelus, Christina, Cantalupo, Paul G., Katz, Joshua P., Cheng, Jingwei, Akagi, Keiko, Thakuria, Manisha, Rabinowits, Guilherme, Wang, Linda C., Symer, David E., Pipas, James M., Harris, Reuben S., DeCaprio, James A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210499/
https://ncbi.nlm.nih.gov/pubmed/28049147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02079-16
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