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Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane

Vasopressin triggers the phosphorylation and apical plasma membrane accumulation of aquaporin 2 (AQP2), and it plays an essential role in urine concentration. Vasopressin, acting through protein kinase A, phosphorylates AQP2. However, the phosphorylation state of AQP2 could also be affected by the a...

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Publicado en:Am J Physiol Renal Physiol
Autores principales: Ren, Huiwen, Yang, Baoxue, Ruiz, Joseph A., Efe, Orhan, Ilori, Titilayo O., Sands, Jeff M., Klein, Janet D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210195/
https://ncbi.nlm.nih.gov/pubmed/27488997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00150.2016
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