Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cells

Vasopressin is the primary hormone regulating urine-concentrating ability. Vasopressin phosphorylates the UT-A1 urea transporter in rat inner medullary collecting ducts (IMCDs). To assess the effect of UT-A1 phosphorylation at S486, we developed a phospho-specific antibody to S486-UT-A1 using an 11...

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Autores principales: Klein, Janet D., Blount, Mitsi A., Fröhlich, Otto, Denson, Chad E., Tan, Xiaoxiao, Sim, Jae H., Martin, Christopher F., Sands, Jeff M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853315/
https://ncbi.nlm.nih.gov/pubmed/20071460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00682.2009
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