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Internalization of UT-A1 urea transporter is dynamin dependent and mediated by both caveolae- and clathrin-coated pit pathways

Dynamin is a large GTPase involved in several distinct modes of cell endocytosis. In this study, we examined the possible role of dynamin in UT-A1 internalization. The direct relationship of UT-A1 and dynamin was identified by coimmunoprecipitation. UT-A1 has cytosolic NH(2) and COOH termini and a l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Haidong, Feng, Xiuyan, Zhuang, Jieqiu, Fröhlich, Otto, Klein, Janet D., Cai, Hui, Sands, Jeff M., Chen, Guangping
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006306/
https://ncbi.nlm.nih.gov/pubmed/20861071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00718.2009
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