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Mature N-linked glycans facilitate UT-A1 urea transporter lipid raft compartmentalization

The UT-A1 urea transporter is a glycoprotein with two different glycosylated forms of 97 and 117 kDa. In this study, we found the 117-kDa UT-A1 preferentially resides in lipid rafts, suggesting that the glycosylation status may interfere with UT-A1 lipid raft trafficking. This was confirmed by a sit...

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Detalhes bibliográficos
Main Authors: Chen, Guangping, Howe, Ashley G., Xu, Gang, Fröhlich, Otto, Klein, Janet D., Sands, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236619/
https://ncbi.nlm.nih.gov/pubmed/21965602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-185991
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