Phosphorylation of UT-A1 urea transporter at serines 486 and 499 is important for vasopressin-regulated activity and membrane accumulation

The UT-A1 urea transporter plays an important role in the urine concentrating mechanism. Vasopressin (or cAMP) increases urea permeability in perfused terminal inner medullary collecting ducts and increases the abundance of phosphorylated UT-A1, suggesting regulation by phosphorylation. We performed...

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Detalhes bibliográficos
Main Authors: Blount, Mitsi A., Mistry, Abinash C., Fröhlich, Otto, Price, S. Russ, Chen, Guangping, Sands, Jeff M., Klein, Janet D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494505/
https://ncbi.nlm.nih.gov/pubmed/18495802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00102.2008
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