Phosphorylation of UT-A1 urea transporter at serines 486 and 499 is important for vasopressin-regulated activity and membrane accumulation

The UT-A1 urea transporter plays an important role in the urine concentrating mechanism. Vasopressin (or cAMP) increases urea permeability in perfused terminal inner medullary collecting ducts and increases the abundance of phosphorylated UT-A1, suggesting regulation by phosphorylation. We performed...

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Autori principali: Blount, Mitsi A., Mistry, Abinash C., Fröhlich, Otto, Price, S. Russ, Chen, Guangping, Sands, Jeff M., Klein, Janet D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494505/
https://ncbi.nlm.nih.gov/pubmed/18495802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00102.2008
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