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Activation of 5-HT and NR2B contributes to visceral hypersensitivity in irritable bowel syndrome in rats

The roles of 5-hydroxytryptamine (5-HT) and spinal N-methyl-D-aspartic acid receptor 2B (NR2B) in visceral hypersensitivity were investigated. A rat model with irritable bowel syndrome (IBS) was established by intracolonic injections of acetic acid onpost-natal days 8-21. Rats were randomly divided...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Chen, Ming-Xian, Chen, Yu, Fu, Rui, Liu, Sai-Yue, Yang, Qin-Qin, Shen, Tang-Biao
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209508/
https://ncbi.nlm.nih.gov/pubmed/28078028
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