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Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome

BACKGROUND: Fecal metabolites are associated with gut visceral sensitivity, mucosal immune function and intestinal barrier function, all of which have critical roles in the pathogenesis of irritable bowel syndrome (IBS). However, the metabolic profile and pathophysiology of IBS are still unclear. We...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Zhang, Wen-Xue, Zhang, Yu, Qin, Geng, Li, Kai-Min, Wei, Wei, Li, Su-Yun, Yao, Shu-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881512/
https://ncbi.nlm.nih.gov/pubmed/31798278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i43.6416
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