Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrhea-predominant irritable bowel syndrome

BACKGROUND: Visceral hypersensitivity is considered to play a vital role in the pathogenesis of irritable bowel syndrome (IBS). Neurotrophins have drawn much attention in IBS recently. Brain-derived neurotrophic factor (BDNF) was found to mediate visceral hypersensitivity via facilitating sensory ne...

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Enregistré dans:
Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Zhang, Yu, Qin, Geng, Liu, De-Rong, Wang, Yan, Yao, Shu-Kun
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2019
Sujets:
Observational Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337018/
https://ncbi.nlm.nih.gov/pubmed/30670915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i2.269
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