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Activation of 5-HT and NR2B contributes to visceral hypersensitivity in irritable bowel syndrome in rats

The roles of 5-hydroxytryptamine (5-HT) and spinal N-methyl-D-aspartic acid receptor 2B (NR2B) in visceral hypersensitivity were investigated. A rat model with irritable bowel syndrome (IBS) was established by intracolonic injections of acetic acid onpost-natal days 8-21. Rats were randomly divided...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Chen, Ming-Xian, Chen, Yu, Fu, Rui, Liu, Sai-Yue, Yang, Qin-Qin, Shen, Tang-Biao
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209508/
https://ncbi.nlm.nih.gov/pubmed/28078028
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