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Activation of 5-HT and NR2B contributes to visceral hypersensitivity in irritable bowel syndrome in rats

The roles of 5-hydroxytryptamine (5-HT) and spinal N-methyl-D-aspartic acid receptor 2B (NR2B) in visceral hypersensitivity were investigated. A rat model with irritable bowel syndrome (IBS) was established by intracolonic injections of acetic acid onpost-natal days 8-21. Rats were randomly divided...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Chen, Ming-Xian, Chen, Yu, Fu, Rui, Liu, Sai-Yue, Yang, Qin-Qin, Shen, Tang-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209508/
https://ncbi.nlm.nih.gov/pubmed/28078028
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