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Methylation of the FOXP3 upstream enhancer as a clinical indicator of defective regulatory T cells in patients with acute coronary syndrome

Atherosclerosis is an immune-mediated inflammatory process, which acts as the main cause of acute coronary syndrome (ACS). Regulatory CD4+CD25+FOXP3+T cells (Tregs) are thought to play a major role in inhibiting the formation and progression of atherosclerosis. However, the exact role played by Treg...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Yang, Jun, Yuan, Xiaoyang, Lv, Caixia, Bai, Rong, Zhang, Le, Ruang, Lei, Zhang, Cuntai, Quan, Xiao-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209483/
https://ncbi.nlm.nih.gov/pubmed/28078003
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