Substrates and Inhibitors of SAMHD1

SAMHD1 hydrolyzes 2'-deoxynucleoside-5'-triphosphates (dNTPs) into 2'-deoxynucleosides and inorganic triphosphate products. In this paper, we evaluated the impact of 2' sugar moiety substitution for different nucleotides on being substrates for SAMHD1 and mechanisms of actions fo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Hollenbaugh, Joseph A., Shelton, Jadd, Tao, Sijia, Amiralaei, Sheida, Liu, Peng, Lu, Xiao, Goetze, Russell W., Zhou, Longhu, Nettles, James H., Schinazi, Raymond F., Kim, Baek
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207538/
https://ncbi.nlm.nih.gov/pubmed/28046007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169052
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