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Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride

The development of the first enantio-, diastereo-, and regioselective iridium-catalyzed allylic alkylation reaction of prochiral enolates to form an all-carbon quaternary stereogenic center with an aliphatic-substituted allylic electrophile is disclosed. The reaction proceeds with good to excellent...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Hethcox, J. Caleb, Shockley, Samantha E., Stoltz, Brian M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207348/
https://ncbi.nlm.nih.gov/pubmed/27891825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609960
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